Cytokeratin MNF 116

Author: Nat Pernick, M.D.

Revised: 24 May 2018, last major update October 2013

Copyright: (c) 2003-2018,, Inc.

PubMed Search: MNF116[title]
Cite this page: Pernick, N. Cytokeratin MNF 116. website. Accessed July 21st, 2018.
Definition / general
  • Broad spectrum cytokeratin marker which stains high and low molecular weight cytokeratins (CK 5, 6, 8, 17 and probably 19)
Uses by pathologists
Positive staining - normal
Positive staining - disease
Negative stains
Microscopic (histologic) images

Images hosted on Pathout server:

Case of the Week #78

Cardiac myxoma with glandular differentiation

Images hosted on other servers:

Anaplastic thyroid carcinoma is MNF116+ (fig A)

Carcinoma in situ and invasive (various)-double immunostaining with collagen type IV

Primary cutaneous
localized amyloidosis:
MNF 116 stains the
amyloid (fig 3)