Multidrug resistance associated protein (MRP)

Author: Kara Hamilton, M.S., Nat Pernick, M.D. (see Authors page)

Revised: 10 November 2015, last major update March 2010

Copyright: (c) 2002-2015,, Inc.

PubMed Search: Multidrug resistance associated protein [title]

Table of Contents
Definition / General
Definition / General
  • 190kDa transmembrane phosphoglycoprotein and member of MRP / ABCC subfamily of ATP binding cassette transporters
  • Overexpressed in various human multidrug resistant tumor cell lines
  • Does not cross react with P-glycoprotein (mdr1, mdr3)
  • Subtypes: