Cite this page: Pernick N. MUC4 (pending). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsmuc4.html. Accessed March 31st, 2020.
Definition / general
- Transmembrane or membrane bound mucin that provides a protective layer of mucus
- Normally acts as barrier to apical surface of epithelial cells, playing a protective and regulatory role
Positive staining - normal
- Tracheobronchial mucosa, colon, stomach, cervix and lung; normal salivary glands
Positive staining - disease
- Pancreatic, colonic, pulmonary and gastric carcinoma