Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 29 September 2013, last major update June 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
PubMed Search: MUC4[title]
- Transmembrane or membrane bound mucin that provides a protective layer of mucus
- Normally acts as barrier to apical surface of epithelial cells, playing a protective and regulatory role
Positive staining - normal
- Tracheobronchial mucosa, colon, stomach, cervix and lung; normal salivary glands
Positive staining - disease
- Pancreatic, colonic, pulmonary and gastric carcinoma
End of Stains > MUC4
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