Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 29 September 2013, last major update June 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
PubMed Search: MUC5AC[title]
Positive staining - normal
- Stomach (foveolar epithelium of body and antrum), tracheobronchial mucosa, endometrium (mucinous metaplasia, eosinophilic change/metaplasia (Mod Pathol 2005;18:1243), surface syncytial change, ciliated change in 52%)
Positive staining - disease
- Extramammary Paget disease, but not mammary Paget disease or normal breast tissue (Am J Surg Pathol 2001;25:1469); mucinous carcinoma of ovary, diffuse-type gastric carcinoma (83%)
Poorly differentiated gastric carcinoma: fig 4b
MUC5AC+ endometrioid endometrial adenocarcinoma (fig 1d)
MUC5AC staining in proliferative endometrium with eosinophilic change
End of Stains > MUC5AC
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