Author: Nat Pernick, M.D. (see Authors page)

Revised: 11 November 2015, last major update June 2005

Copyright: (c) 2002-2015,, Inc.

PubMed Search: Myeloperoxidase [title]

Definition / General
  • Staining is either immunohistochemistry (IHC) or enzyme cytochemistry - enzyme cytochemistry is most sensitive and specific stain for myeloid leukemias and granulocytic sarcoma
  • Stains neutrophils strongly (diffuse granular pattern), other granulocytes variably
Micro Images
Missing Image

Myeloid sarcoma of breast

Positive Staining - Normal
  • Neutrophils, eosinophils, monocytes (variable), AML-M1, M2, microgranular M3
  • Granulocytic sarcoma
Negative Staining
  • Lymphocytes, ALL