Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 29 September 2013, last major update June 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
PubMed Search: Myeloperoxidase[title]
- Staining is either immunohistochemistry (IHC) or enzyme cytochemistry - enzyme cytochemistry is most sensitive and specific stain for myeloid leukemias and granulocytic sarcoma
- Stains neutrophils strongly (diffuse granular pattern), other granulocytes variably
Positive staining - enzyme cytochemistry
- Neutrophils, eosinophils, monocytes (variable), AML-M1, M2, microgranular M3
Positive staining - immunohistochemistry
Negative staining - enzyme cytochemistry
Granulocytic sarcoma (IHC)
Myeloid sarcoma of breast (fig 5. IHC)
End of Stains > Myeloperoxidase
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