Stains
Myogenin

Author: Nat Pernick, M.D. (see Authors page)

Revised: 11 November 2015, last major update June 2005

Copyright: (c) 2002-2015, PathologyOutlines.com, Inc.

PubMed Search: Myogenin [title]

Definition / General
  • Myogenic transcriptional regulatory protein expressed early in skeletal muscle differentiation
  • Sensitive and specific for rhabdomyosarcoma
  • Focal nuclear staining in desmoid tumors, infantile myofibromatosis, synovial sarcoma, infantile fibrosarcoma, entrapped atrophic or regenerative skeletal muscle (Am J Surg Pathol 2001;25:1150)
Micro Images
Missing Image

Hepatorenal embryonal rhabdomyosarcoma

Positive Staining - Normal
  • Normal fetal muscle
Negative Staining
  • Normal adult muscle