Author: Nat Pernick, M.D. (see Authors page)

Revised: 11 November 2015, last major update June 2005

Copyright: (c) 2002-2015,, Inc.

PubMed Search: Myogenin [title]

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Cite this page: Myogenin. website. Accessed January 23rd, 2019.
Definition / general
  • Myogenic transcriptional regulatory protein expressed early in skeletal muscle differentiation
  • Sensitive and specific for rhabdomyosarcoma
  • Focal nuclear staining in desmoid tumors, infantile myofibromatosis, synovial sarcoma, infantile fibrosarcoma, entrapped atrophic or regenerative skeletal muscle (Am J Surg Pathol 2001;25:1150)
Microscopic (histologic) images
Missing Image

Hepatorenal embryonal rhabdomyosarcoma

Positive staining - normal
  • Normal fetal muscle
Negative staining
  • Normal adult muscle