Topic Completed: 1 June 2005

Minor changes: 28 August 2020

Copyright: 2002-2020,, Inc.

PubMed Search: Myogenin [title]

Nat Pernick, M.D.
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Cite this page: Pernick N. Myogenin. website. Accessed September 21st, 2020.
Definition / general
  • Myogenic transcriptional regulatory protein expressed early in skeletal muscle differentiation
  • Sensitive and specific for rhabdomyosarcoma
  • Focal nuclear staining in desmoid tumors, infantile myofibromatosis, synovial sarcoma, infantile fibrosarcoma, entrapped atrophic or regenerative skeletal muscle (Am J Surg Pathol 2001;25:1150)
Positive staining - normal
  • Normal fetal muscle
Negative staining
  • Normal adult muscle
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