Stains
NF2


Topic Completed: 1 June 2005

Revised: 7 March 2019

Copyright: 2002-2015, PathologyOutlines.com, Inc.

PubMed Search: NF2 [title]


Nat Pernick, M.D.
Page views in 2018: 83
Page views in 2019 to date: 82
Table of Contents
Definition / general
Cite this page: Pernick N. NF 2. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsnf2.html. Accessed September 18th, 2019.
Definition / general
  • Tumor suppressor protein at 22q11-13.1
  • Produces protein called merlin or schannomin
  • Deleted in soft tissue perineurioma
  • Both copies inactivated in up to 60% of sporadic meningiomas
  • Often no protein expression in schwannoma
  • May be involved in tumorigenesis of schwannoma and some meningiomas
Back to top