Topic Completed: 1 November 2013

Minor changes: 28 August 2020

Copyright: 2002-2020,, Inc.

PubMed Search: Olig2 [title]

Nat Pernick, M.D.
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Cite this page: Pernick N. Olig2. website. Accessed September 26th, 2020.
Definition / general
Clinical features
Uses by pathologists
Microscopic (histologic) images

Images hosted on other servers:
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Pediatric glioblastoma

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Pediatric ependymoma

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Pediatric glioma, KI-67

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Pilocytic astrocytomas

Positive staining - disease
  • Adult gliomas: diffuse (nearly all)
  • Glioblastoma variants:
    • Giant cell (67%)
    • Gliosarcoma (93% in glial component, 14% in sarcomatous component)
    • Granular cell (100%)
    • Small cell (98%), with oligodendroglial component (100%), with PNET-like foci (74%, staining in PNET-like foci) (Mod Pathol 2013;26:315)
    Pediatric gliomas: pilocytic astrocytoma, diffuse-type astrocytic tumors (WHO grades II-IV) (J Neurooncol 2011;104:423)
  • Glioneuronal tumors: dysembryoplastic neuroepithelial tumor, papillary glioneuronal tumor, rosette-forming glioneuronal tumor of fourth ventricle (Neuropathology 2013;33:246)
  • Oligodendroglioma
Negative staining
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