Stains
OPA1


Topic Completed: 1 January 2013

Revised: 7 March 2019

Copyright: 2002-2015, PathologyOutlines.com, Inc.

PubMed Search: OPA1 [title]

Nat Pernick, M.D.
Page views in 2018: 4
Page views in 2019 to date: 16
Cite this page: Pernick N. OPA1. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsopa1.html. Accessed September 16th, 2019.
Definition / general
  • Optic atrophy 1 protein (OPA1): 112 kd guanosine triphosphatase involved in mitochondrial inner membrane fusion and anticancer drug-mediated cytotoxicity
  • Associated with autosomal dominant optic atrophy, characterized by selective degeneration of retinal ganglion cells (Jpn J Ophthalmol 2012;56:91, J Neurol Sci 2012;315:146)
Uses by pathologists
  • No significant current use
Positive staining - disease
Electron microscopy images
Missing Image

Loss of OPA

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