p27 kip1

Author: Nat Pernick, M.D. (see Authors page)

Revised: 10 November 2015, last major update June 2005

Copyright: (c) 2003-2015,, Inc.

PubMed Search: p27[title]

Definition / General
  • Cyclin dependent kinase inhibitor leading to cell cycle arrest in G1 phase
  • Member of Cip/Kip family of proteins
  • Loss or reduced expression is associated with poor outcome in carcinoma of breast, prostate, GI tract and lung
  • Nuclear stain