Stains
p27 kip1

Author: Nat Pernick, M.D. (see Authors page)

Revised: 10 November 2015, last major update June 2005

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: p27[title]


Cite this page: p27 kip1. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsp27.html. Accessed December 7th, 2016.
Definition / General
  • Cyclin dependent kinase inhibitor leading to cell cycle arrest in G1 phase
  • Member of Cip/Kip family of proteins
  • Loss or reduced expression is associated with poor outcome in carcinoma of breast, prostate, GI tract and lung
Interpretation
  • Nuclear stain