Stains
p27 kip1


Topic Completed: 1 June 2005

Revised: 6 March 2019

Copyright: 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: p27[title]

Nat Pernick, M.D.
Page views in 2018: 293
Page views in 2019 to date: 190
Cite this page: Pernick N. p27 kip1. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsp27.html. Accessed August 22nd, 2019.
Definition / general
  • Cyclin dependent kinase inhibitor leading to cell cycle arrest in G1 phase
  • Member of Cip/Kip family of proteins
  • Loss or reduced expression is associated with poor outcome in carcinoma of breast, prostate, GI tract and lung
Interpretation
  • Nuclear stain
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