Cite this page: Pernick N. RAD51. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsrad51.html. Accessed March 23rd, 2019.
Definition / general
- Plays major role in homologous recombination of DNA during double strand break repair (Wikipedia: RAD51 [Accessed 9 August 2018], GeneCards: RAD51 [Accessed 9 August 2018])
- Disassembles nucleosomes by unwrapping DNA from histones (Nucleic Acids Res 2013;41:7302)
- Interacts with BRCA2 and BRCA1
- Protein highly conserved in most eukaryotes, from yeast to humans