Author: Nat Pernick, M.D. (see Authors page)

Revised: 10 July 2018, last major update September 2013

Copyright: (c) 2002-2018,, Inc.

PubMed Search: ROS1[title]

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Cite this page: Pernick, N. ROS1. website. Accessed January 18th, 2019.
Definition / general
Uses by pathologists
  • ROS1 immunostains are 100% sensitive and 92% specific for ROS1 rearrangements by FISH, making it an effective screening tool for lung adenocarcinoma (Am J Surg Pathol 2013;37:1441)
Microscopic (histologic) images

Images hosted on other servers:

Invasive ductal carcinoma (ROS1+, fig B)

Non small cell lung cancer

ROS1 rearranged lung tumors