Stains & molecular markers

Topic Completed: 1 November 2013

Minor changes: 30 September 2020

Copyright: 2013-2020,, Inc.

PubMed Search: SOX9[title]

Nat Pernick, M.D.
Page views in 2019: 816
Page views in 2020 to date: 939
Cite this page: Pernick N. SOX9. website. Accessed October 25th, 2020.
Definition / general
  • Sex determining region Y (SRY)-related high mobility groupbox 9
  • Transcription factor linked to hedgehog pathways, plays a central role in development and differentiation of multiple cell lineages
  • Downstream molecule of beta-catenin
  • Master regulator of chondrogenesis
Clinical features
Uses by pathologists
Microscopic (histologic) images

Images hosted on other servers:

Duodenum: normal mucosa
(figs D, E, F)

Duodenum: nonampullary adenoma
(figs D, E, F)

Duodenum: nonampullary adenocarcinoma (figs D, E, F)

Liver: hepatocellular carcinoma and normal

Lung: normal and non small cell lung cancer

Skin: scalp

Skin : psoriasis, keratoacanthoma, carcinoma

Skin: TISH analysis

Testis: androgen insensitivity and Sertoli cell only syndromes, normal spermatogenesis

Back to top
Image 01 Image 02