Stains Chapter
SOX9

Author: Nat Pernick, M.D. (see Authors page)

Revised: 11 December 2015, last major update November 2013

Copyright: (c) 2013-2015, PathologyOutlines.com, Inc.

PubMed Search: SOX9[title]

General
  • Sex determining region Y (SRY)-related high mobility groupbox 9
  • Transcription factor linked to hedgehog pathways, plays a central role in development and differentiation of multiple cell lineages
  • Downstream molecule of beta-catenin
  • Master regulator of chondrogenesis
Clinical Features
Uses by Pathologists
Micro Images

Images hosted on other servers:

Duodenum: normal mucosa
(figs D, E, F)

Duodenum: nonampullary adenoma
(figs D, E, F)

Duodenum: nonampullary adenocarcinoma (figs D, E, F)

Liver: hepatocellular carcinoma and normal

Lung: normal and non small cell lung cancer

Skin: scalp

Skin : psoriasis, keratoacanthoma, carcinoma

Skin: TISH analysis

Testis: androgen insensitivity and Sertoli cell only syndromes, normal spermatogenesis