Author Nat Pernick, M.D. (see Authors page)

Revised: 10 December, last major update June 2005

Copyright: (c) 2003-2015,, Inc.

PubMed Search: Survivin[title]

Cite this page: Survivin. website. Accessed June 19th, 2018.
Definition / general
  • Inhibitor of apoptosis protein; may also enhance proliferative activity of tumor cells
  • Overexpression enhances cell survival
  • Cytoplasmic staining
Positive staining - normal
  • Fetal tissues
Positive staining - disease
  • Hepatocellular carcinoma, endometrial carcinoma
Negative staining
  • Most normal, terminally differentiated tissue