Stains
T-bet



Topic Completed: 1 December 2011

Revised: 8 March 2019

Copyright: 2002-2015, PathologyOutlines.com, Inc.
Page views in 2018: 134
Page views in 2019 to date: 75
Cite this page: Pernick N. T-bet. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainstbet.html. Accessed May 24th, 2019.
Definition / general
  • Master regulator of helper T cells type 1
  • As a transcription factor, also regulates development and cytotoxic function of NK cells
Uses by pathologists
Microscopic (histologic) images

Image hosted on other servers:

Pre-B lymphoblastic lymphoma of kidney (left), skin (right)

Positive staining - normal
  • CD4+ T cells, some B cells
Positive staining - disease
Back to top