Stains
Tenascin

Author: Nat Pernick, M.D. (see Authors page)

Revised: 7 December 2015, last major update June 2005

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: Tenascin[title]

Table of Contents
Definition / General
Cite this page: Tenascin. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainstenascin.html. Accessed December 6th, 2016.
Definition / General
  • Also called tenascin C
  • Large glycoprotein of extracellular matrix, synthesized by fibroblasts, composed of epidermal growth factor like repetitions
  • May function in epithelial-mesenchymal interactions
  • Expressed during embryogenesis, growth, wound healing, inflammation
  • Increased in carcinoma of Ampulla of Vater, breast, colon, lung, prostate
  • Pheochromocytoma: strong expression associated with malignancy (Am J Surg Pathol 2001;25:1419)