Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 6 September 2013, last major update June 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
PubMed Search: Tenascin[title]
- Also called tenascin C
- Large glycoprotein of extracellular matrix, synthesized by fibroblasts, composed of epidermal growth factor like repetitions
- May function in epithelial-mesenchymal interactions
- Expressed during embryogenesis, growth, wound healing, inflammation
- Increased in carcinoma of Ampulla of Vater, breast, colon, lung, prostate
- Pheochromocytoma: strong expression associated with malignancy (Am J Surg Pathol 2001;25:1419)
End of Stains > Tenascin
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