Author: Nat Pernick, M.D. (see Authors page)

Revised: 26 January 2017, last major update June 2013

Copyright: (c) 2002-2017,, Inc.

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Cite this page: Thyroglobulin. website. Accessed January 22nd, 2019.
Definition / general
  • Large glycoprotein (MW 670K) produced by thyroid follicular cells; later iodinated to form T3 and T4
  • Specific marker of thyroid differentiation
Microscopic (histologic) images
Images hosted on PathOut server:

Thyroid gland signet ring
follicular adenoma is thyroglobulin+

Courtesy of Andrey Bychkov, M.D., Ph.D.:

Expression in thyroid

Easily leaks into soft tissue

Solid cell nests