Stains
Tubulin

Author: Nat Pernick, M.D. (see Authors page)

Revised: 8 December 2015, last major update June 2005

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

Definition / General
  • Structural protein involved in assembly of mitotic spindles
  • Increased expression is associated with increased mitotic activity
Interpretation
  • Cytoplasmic staining in mantle cell lymphoma
Positive Staining - Normal
  • Germinal centers (but not mantle zones) of benign lymph nodes
Micro Images

Image hosted on Nature.com:

Staining in tonsil (fig 2a), mantle cell lymphoma (2d)