Author: Nat Pernick, M.D. (see Authors page)

Revised: 8 December 2015, last major update June 2005

Copyright: (c) 2003-2015,, Inc.

Cite this page: Tubulin. website. Accessed March 19th, 2018.
Definition / general
  • Structural protein involved in assembly of mitotic spindles
  • Increased expression is associated with increased mitotic activity
  • Cytoplasmic staining in mantle cell lymphoma
Positive staining - normal
  • Germinal centers (but not mantle zones) of benign lymph nodes
Microscopic (histologic) images

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Staining in tonsil (fig 2a), mantle cell lymphoma (2d)