Stains
Tyrosinase

Author: Lauren Stuart, M.D., M.B.A. (see Authors page)

Revised: 10 August 2018, last major update May 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Tyrosinase[TI] review[ptyp]

Cite this page: Stuart, L. Tyrosinase. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainstyrosinase.html. Accessed August 17th, 2018.
Definition / general
  • Also called T311 (for immunohistochemistry)
  • Melanocyte specific antigen important in melanin synthesis and melanosome formation
  • Interpretation: cytoplasmic staining
Uses by pathologists
  • Identification of melanocytic neoplasms
Microscopic (histologic) images

Images hosted on other servers:

Normal skin
prominent melanocytes (a);
melanoma - positive
homogenous tumor cells (b)

Melanoma (image 3, cytology)

Renal angiomyolipoma (image 4, weak)

Positive staining - normal
Positive staining - disease
Negative staining