Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 2 November 2015, last major update June 2005
Copyright: (c) 2003-2015,, Inc.
Definition / General
  • Triggers pathway for protein degradation associated with turning on and off cell cycle regulators
  • Can turn on cyclin-CDK complexes by destroying its inhibitor
Micro Images

Neuronal inclusion staining in motor neuron disease