Stains
VEGF


Topic Completed: 1 June 2005

Minor changes: 28 August 2020

Copyright: 2003-2020, PathologyOutlines.com, Inc.

Nat Pernick, M.D.
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Table of Contents
Definition / general
Cite this page: Pernick N. VEGF. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsvegf.html. Accessed September 26th, 2020.
Definition / general
  • Vascular Endothelial Growth Factor
  • Exists in 4 different homodimeric isoforms due to alternate splicing
  • Potent angiogenic growth factor that stimulates endothelial cell proliferation and induces microvessel permeability
  • Protein and mRNA are overexpressed in various tumors
  • May have prognostic significance in esophageal adenocarcinoma (Hum Pathol 2005;36:955)
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