Wright-Giemsa stain

Topic Completed: 1 June 2005

Minor changes: 28 August 2020

Copyright: 2003-2020,, Inc.

Nat Pernick, M.D.
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Table of Contents
Definition / general
Cite this page: Pernick N. Wright-Giemsa stain. website. Accessed October 26th, 2020.
Definition / general
  • Also called Wright’s stain
  • A "Romanowsky-type" stain, composed of mixtures of methylene blue, azure and eosin compounds
  • Used to stain peripheral blood smears
  • Methylene blue is a metachromatic stain, meaning that some tissue components (mast cell granules, cartilage, mucin, amyloid) stain purple and not blue
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