Wright-Giemsa stain

Author: Nat Pernick, M.D. (see Authors page)
Revised: 30 November 2015, last major update June 2005
Copyright: (c) 2003-2015,, Inc.

Definition / General
  • Also called Wright’s stain
  • A "Romanowsky-type" stain, composed of mixtures of methylene blue, azure and eosin compounds
  • Used to stain peripheral blood smears
  • Methylene blue is a metachromatic stain, meaning that some tissue components (mast cell granules, cartilage, mucin, amyloid) stain purple and not blue
Micro Images

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Peripheral blood smear, Wright's stain