Stomach
Gastritis
Acute gastric ulcer

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 29 November 2016, last major update July 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: acute gastric ulcer[title]
Cite this page: Acute gastric ulcer. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stomachacutegastriculcer.html. Accessed December 6th, 2016.
Definition / General
  • Also called stress ulcer
  • Severe form of acute gastritis in which erosion reaches muscularis mucosa
  • Some authors consider large erosions to be stress ulcers
  • If underlying condition resolves, complete healing occurs
  • Common autopsy finding
  • Causes: NSAIDs, steroids, severe physiologic stress (shock, extensive burns, sepsis, severe trauma, increased intracranial pressure, post-intracranial surgery, intensive care unit), systemic amyloidosis, post-chemotherapy, radiation therapy
  • Complications: bleeding (may be massive; 1-4% of patients require transfusion), perforation, obstruction from edema / scarring

  • Specific forms:
    • Curling ulcer: severe burns and duodenal ulcer
    • Cushing ulcer: increased intracranial pressure and gastric, esophageal, or duodenal ulcers
Gross Images

Images hosted on other servers:

Various images

Micro Description
  • Usually < 1 cm, often multiple, small brown circular ulcer base (digested blood) anywhere in stomach
  • No induration of margins of ulcer - abrupt lesions with normal adjacent mucosa; no scarring or blood vessel thickening
Micro Images

Images hosted on other servers:

Various images