Home   Chapter Home   Jobs   Conferences   Fellowships   Books




Collagenous gastritis

Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 5 August 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.


● Very rare
● Children and young adults with severe anemia, nodular endoscopic pattern
● Associated with collagenous colitis in adults with chronic watery diarrhea or with celiac disease
● Case reports in patients with celiac disease (Arch Pathol Lab Med 2001;125:1579, Mod Pathol 2000;13:591)


● Erosion and hemorrhages in children

Micro description

● Thick subepithelial collagen band (at least 10 microns, mean 30 microns, normal is 1 micron), often ragged at lower edge, commonly with entrapped red blood cells, fibroblasts, inflammatory cells and superficial capillaries (Am J Surg Pathol 2001;25:1174)
● Associated with mixed inflammatory infiltrate of lamina propria and variable surface epithelial damage of cuboidal cytoplasmic changes, reactive cytoplasmic changes, reactive nuclear enlargement, subepithelial edema and erosions
● Similar changes occur after radiation therapy and in some patients with scleroderma

Micro images

Various images

Celiac disease

End of Stomach > Gastritis > Collagenous gastritis

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at [email protected] with any questions (click here for other contact information).