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Stomach
Gastric Giardiasis
Author: Nat Pernick, M.D, and Kara Hamilton, M.S., PathologyOutlines.com, Inc.
Revised: 16 September 2009
Last major update: September 2009
Copyright: (c) 2002-2009, PathologyOutlines.com, Inc.
Definition
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● Caused by Giardia lamblia
● Often associated with H. pylori infection (J Clin Pathol 1992;45:964)
● See also Small Intestine
Clinical
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● Severe diarrhea, vomiting, abdominal cramps, fever
● Also anorexia, malaise, fatigue
● Associated with chronic atrophic gastritis (J Egypt Soc Parasitol 1996;26:481)
● Recommended to search carefully for giardia in patients with chronic atrophic gastritis, as it may cause persistent upper GI symptoms even after H. pylori eradication (Indian J Pathol Med 2006;49:519)
Case reports
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● 20 year old woman with dyspepsia (Case of the Week #157)
Treatment
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● Metronidazole or other antibiotics (eMedicine)
Microscopic description
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● Trophozoites are sickle or teardrop shaped and can be found along the surface of the foveolar epithelial cells
Micro images
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Giardial trophozoites along the surface Sickle-shaped trophozoites
of foveolar epithelial cells
Small intestinal giardia Pear-shaped trophozoites
from stool
Positive stains
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● Trichrome with iron-hematoxylin counterstain
● Giemsa stain
Differential diagnosis
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● H. pylori associated follicular gastritis
End of Stomach > Gastric Giardiasis
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