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Stromal / other tumors

Gastrointestinal stromal tumor - Staging

Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 13 October 2012, last major update July 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Also applies to GIST of omentum

Primary tumor (T)
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TX: Primary tumor cannot be assessed
T0: No evidence for primary tumor
T1: Tumor 2 cm or less
T2: Tumor more than 2 cm but not more than 5 cm
T3: Tumor more than 5 cm but not more than 10 cm
T4: Tumor more than 10 cm in greatest dimension

Regional lymph nodes (N)
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NX: Regional lymph nodes cannot be assessed
N0: No regional lymph node metastasis
N1: Regional lymph node metastasis

Distant Metastasis (M)
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M0: No distant metastasis
M1: Distant metastasis

Anatomic stage / prognostic groups
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Stage IA: T1-2 N0 M0 low mitotic rate
Stage IB: T3 N0 M0 low mitotic rate
Stage II: T1-2 N0 M0 high mitotic rate or T4 N0 M0 low mitotic rate
Stage IIIA: T3 N0 M0 high mitotic rate
Stage IIIB: T4 N0 M0 high mitotic rate
Stage IV: N1 or M1

● Low mitotic rate: 5 or fewer per 50 HPF
● High mitotic rate: over 5 per 50 HPF

End of Stomach > Stromal / other tumors > Gastrointestinal stromal tumor - Staging

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