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Stomach

Gastritis

Granulomatous gastritis


Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 5 August 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

Causes
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● Anisakiasis, common variable immunodeficiency, Crohn’s disease, foreign body, histoplasmosis, idiopathic, post-barium studies, sarcoidosis, tuberculosis, tumors (extravasated mucin), vasculitis
● Rarely Langerhans cell histiocytosis

Idiopathic / isolated:
● Usually older white men vs. sarcoid (often young black men/women), other causes of granulomatous disease must be excluded
● Patients may later develop Crohn’s disease or sarcoidosis
● A descriptive diagnosis such as gastric mucosa with non-necrotizing granulomatous inflammation and a recommendation for followup may be more prudent than a diagnosis of idiopathic granulomatous gastritis

Chronic granulomatous disease
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● May present with distinct or poorly formed granulomas in children with pigment-laded macrophages
● Associated with outlet obstruction (Am J Surg Pathol 1982;6:673)

End of Stomach > Gastritis > Granulomatous gastritis


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