Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Stomach

Polyps

Inflammatory fibroid polyp


Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 8 August 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Formerly called eosinophilic granuloma
● Non-neoplastic / benign polyp that occurs anywhere in GI tract, but most common in stomach and small intestine
● Usually 50-60 years old
● Associated with achlorhydria, hypochlorhydria, pyloric obstruction
● Usually antral
● May occlude pyloric channel
● Rarely associated with adenocarcinoma or adenoma (Arch Pathol Lab Med 1988;112:829)

Treatment
=========================================================================

● Local excision

Gross description
=========================================================================

● Sessile or pedunculated
● Median size 1.5 cm, largest was 9 cm

Micro description
=========================================================================

● Submucosal lesion with whorls of granulation tissue-like vessels, fibroblastic cells and prominent inflammatory response, primarily eosinophils
● Also plasma cells and mast cells
● Minimal mitotic activity

Micro images
=========================================================================


   
Various images


CD34


CD117

Positive stains
=========================================================================

● Vimentin (100%), CD34, variable smooth muscle actin, HHF-35, fascin, CD35, cyclin D1, calponin

Negative stains
=========================================================================

● CD117 (although mast cells are CD117+), S100

Additional references
=========================================================================

Am J Surg Pathol 1993;17:1159, Mod Pathol 2000;13:1134, Mod Pathol 2003;16:366

End of Stomach > Polyps > Inflammatory fibroid polyp


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).