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Juvenile polyp

Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 8 August 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.


● Also called retention polyp
● Part of generalized juvenile polyposis coli or rare gastric subtype, 20-50% of patients with syndrome have gastric polyps
● Syndrome due to genetic dysregulation of TGF-β pathway
● Associated with increased risk of colorectal and gastric carcinoma

Gross description

● Smooth surfaced, 1-2 cm, short narrow stalk

Micro description

● Irregular cysts in lamina propria with normal gastric epithelium
● Surface and foveolar hyperplasia, may have stromal hemorrhage, surface ulceration and chronic inflammation due to torsion

Micro images

Gastric juvenile polyp

Differential diagnosis

● Hyperplastic polyp: usually background mucosal disease, may need clinical or family history for definitive diagnosis

End of Stomach > Polyps > Juvenile polyp

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