Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 26 September 2012, last major update September 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
● 55-75% of primary gastrointestinal lymphomas are gastric
● Lymphomas are 1-7% of gastric malignancies
● Diffuse large B-cell lymphoma most common, then extranodal marginal zone (MALT) lymphoma
● Most patients age 60+
● Clinically resembles carcinoma, but usually better prognosis
● Associated with erosion (61%), intestinal metaplasia (59%), H. pylori (57%), atrophy (37%), dysplasia (4%) (Arch Pathol Lab Med 2000; 124:1628)
● Diffuse large B cell lymphoma generally resembles nodal disease
● Features highly suggestive of low grade lymphoma versus inflammation are dense lymphoid infiltrates with either prominent lymphoepithelial lesions, moderate cytologic atypia, or Dutcher bodies (Am J Surg Pathol 1990;14:1087)
End of Stomach > Lymphoma > General
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