Stomach
Gastritis
Malakoplakia

Authors: Elliot Weisenberg, M.D. (see Authors page)

Revised: 23 November 2016, last major update August 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: gastric malakoplakia
Cite this page: Malakoplakia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stomachmalakoplakia.html. Accessed December 5th, 2016.
Definition / General
  • May involve any part of GI tract, very rare
  • Associated with E. coli, Klebsiella, Yersinia, Mycobacteria and R. equi
  • Case report associated with gastric adenocarcinoma (Arch Pathol Lab Med 1978;102:136)
Gross Description
  • Slightly elevated plaque with umbilication of overlying mucosa
Micro Description
  • Submucosal histiocytes with cytoplasmic inclusions (Michaelis-Gutmann bodies) that are positive for calcium with von Kossa stain
Electron Microscopy Description
  • Inclusions have dense central calcified body and concentric alternating rings