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Stomach

Gastritis

Malakoplakia

Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 5 August 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● May involve any part of GI tract, very rare
● Associated with E. coli, Klebsiella, Yersinia, mycobacteria, and R. equi
● Case report associated with gastric adenocarcinoma (Arch Pathol Lab Med 1978;102:136)

Gross description
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● Slightly elevated plaque with umbilication of overlying mucosa

Micro description
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● Submucosal histiocytes with cytoplasmic inclusions (Michaelis-Gutmann bodies) that are positive for calcium with von Kossa stain

Electron microscopy description
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● Inclusions have dense central calcified body and concentric alternating rings

End of Stomach > Gastritis > Malakoplakia

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