
Home
Chapter Home
Jobs
Conferences
Fellowships
Books
Advertisement
Stomach
Carcinoma
Oncocytic adenocarcinoma
Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 28 September 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
General
=========================================================================
● Rare, <50 cases reported
● Also called parietal cell/gland carcinoma
● Elderly patients, ages 58-81 years
● Resemble parietal cells, but antiparietal cell antibodies often nonreactive (Am J Surg Pathol 2002;26:458)
● Cases from other studies may have parietal cell origin, but need antiparietal cell antibody testing
Micro description
=========================================================================
● Moderate to well differentiated adenocarcinoma with sheets of cells with abundant eosinophilic, finely granular cytoplasm resembling parietal cells
Positive stains
=========================================================================
● PTAH, Luxol fast blue
Negative stains
=========================================================================
● PAS, Alcian blue, MUC2 (rare cells may be positive)
Electron microscopy description
=========================================================================
● Abundant mitochondria, tubulovesicles, intracellular canaliculi, intercellular lumina with long microvilli
End of Stomach > Carcinoma > Oncocytic adenocarcinoma
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com
with any questions (click here for other
contact information).