Stromal / other tumors
Plexiform fibromyxoma

Topic Completed: 1 October 2014

Revised: 22 March 2019

Copyright: 2003-2019,, Inc.

PubMed Search: gastric plexiform fibromyxoma

Nat Pernick, M.D.
Page views in 2018: 2,131
Page views in 2019 to date: 1,133
Cite this page: Pernick N. Plexiform fibromyxoma. website. Accessed June 20th, 2019.
Definition / general
Case reports
Clinical images

Case of the Week #330 (endoscopy image)

72 year old woman

Microscopic (histologic) description
  • Multinodular proliferation of bland myofibroblastic cells and arborizing capillaries in a myxoid stroma (World J Gastroenterol 2010;16:2835)
  • Proliferation of cytologically bland spindle cells with a myxoid background
  • No mitoses
Microscopic (histologic) images

Case of the Week #316







Case of the Week #330

Actin (left); caldesmon (right)

Positive stains
Negative stains
  • Desmin, S100, CD34, c-kit and DOG1
  • Ki67 demonstrates a very low proliferation index
  • Prominent arborizing capillaries are highlighted by CD34
Differential diagnosis
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