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Pseudomembranous gastritis

Reviewers: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 5 August 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.


● Case report of 36 year old man, post-BMT with GVHD and Aspergillus infection that involved the stomach and lungs without evidence of C. difficile or disease in esophagus or intestines (Arch Pathol Lab Med 2000;124:619)
● Pseudomembranes also caused by chronic erosions, ischemia

Gross description

Case Report above:
● Gastric mucosa covered by 1.5 cm thick pseudomembrane containing Aspergillus, with friable yellow mucoid material and multiple hemorrhagic foci

Micro description

Case Report above:
● Fibrin, mucus, neutrophils, fungal hyphae with acute angle branching consistent with Aspergillus
● Distended gastric glands extended to pseudomembrane in volcano-like appearance
● Hemorrhagic necrosis common with “ghost” (necrotic) gastric glands

Micro images

Various images

End of Stomach > Gastritis > Pseudomembranous gastritis

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