Pseudomembranous gastritis

Authors: Elliot Weisenberg, M.D. (see Authors page)

Revised: 23 November 2016, last major update August 2012

Copyright: (c) 2003-2016,, Inc.

PubMed Search: pseudomembranous gastritis
Cite this page: Pseudomembranous gastritis. website. Accessed November 14th, 2018.
Definition / general
  • Pseudomembranes also caused by chronic erosions, ischemia
Case reports
  • 36 year old man, post-BMT with GVHD and Aspergillus infection that involved the stomach and lungs without evidence of C. difficile or disease in esophagus or intestines (Arch Pathol Lab Med 2000;124:619)
Gross description
  • Gastric mucosa covered by 1.5 cm thick pseudomembrane containing Aspergillus, with friable yellow mucoid material and multiple hemorrhagic foci (Arch Pathol Lab Med 2000;124:619)
Microscopic (histologic) description
  • Fibrin, mucus, neutrophils, fungal hyphae with acute angle branching consistent with Aspergillus
  • Distended gastric glands extended to pseudomembrane in volcano-like appearance
  • Hemorrhagic necrosis common with "ghost" (necrotic) gastric glands
  • Reference: Arch Pathol Lab Med 2000;124:619
Microscopic (histologic) images

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