Staging - Neuroendocrine tumors

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 19 December 2016, last major update July 2012

Copyright: (c) 2003-2016,, Inc.

PubMed Search: staging neuroendocrine tumors
Cite this page: Staging - Neuroendocrine tumors. website. Accessed July 23rd, 2018.
Primary tumor (T)
  • TX: Primary tumor cannot be assessed
  • T0: No evidence of primary tumor
  • Tis: Carcinoma in situ / dysplasia (tumor size less than 0.5 mm), confined to mucosa
  • T1: Tumor invades lamina propria or submucosa and 1 cm or less in size
  • T2: Tumor invades muscularis propria or more than 1 cm in size
  • T3: Tumor penetrates subserosa
  • T4: Tumor invades visceral peritoneum (serosal) or other organs or adjacent structures

  • Note: For any T, add (m) for multiple tumors
Regional lymph nodes (N)
  • NX: Regional lymph nodes cannot be assessed
  • N0: No regional lymph node metastasis
  • N1: Regional lymph node metastasis
Distant metastasis (M)
  • M0: No distant metastasis
  • M1: Distant metastasis
Anatomic stage / prognostic groups
  • Stage 0: Tis N0 M0
  • Stage I: T1 N0 M0
  • Stage IIA: T2 N0 M0
  • Stage IIB: T3 N0 M0
  • Stage IIIA: T4 N0 M0
  • Stage IIIB: Any T N1 M0
  • Stage IV: M1 (any T, any N)