Syphilitic gastritis

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 2 December 2016, last major update August 2012

Copyright: (c) 2003-2016,, Inc.

PubMed Search: syphilitic gastritis
Cite this page: Syphilitic gastritis. website. Accessed November 14th, 2018.
Definition / general
  • Rare, stomach involved in < 1% of cases
  • Gastric involvement may occur in secondary and tertiary syphylis
Gross description
  • Erosions or ulcers in pyloric region, progressing to shrunken fibrotic stomach resembling linitis plastica
Microscopic (histologic) description
  • Ulcers, abundant plasma cells, fibrosis
  • Variable endarteritis obliterans, poorly formed granulomas (gummas)
Positive stains
  • Steiner silver stain identifies spirochetes