Other nonneoplastic lesions

Topic Completed: 1 August 2012

Revised: 20 March 2019

Copyright: 2003-2019,, Inc.

PubMed Search: gastric xanthoma

Elliot Weisenberg, M.D.
Page views in 2018: 4,581
Page views in 2019 to date: 4,640
Cite this page: Weisenberg E. Xanthoma. website. Accessed November 15th, 2019.
Definition / general
  • Also known as xanthelasma, lipid islands
  • Common in Japan
  • May be due to bile reflux
  • No clinical significance
Case reports
Gross description
  • Small yellow / cream colored intramucosal lesion, < 5 mm, single or multiple
Microscopic (histologic) description
  • Foamy histiocytes with neutral fat in the lamina propria
Negative stains
  • PAS
Differential diagnosis
  • Signet ring cell carcinoma
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