Testis and epididymis
Intersex syndromes
Congenital adrenal hyperplasia

Author: Turki Al-Hussain, M.D. (see Authors page)

Revised: 5 April 2017, last major update September 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Congenital adrenal hyperplasia [title] men

Table of Contents
Definition / general
Cite this page: Congenital adrenal hyperplasia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/testisCAH.html. Accessed July 21st, 2017.
Definition / general
  • Autosomal recessive, due to various enzymatic defects that cause different patterns of synthesis of glucocortical, mineralocorticoid and sex hormone synthesis
  • Genetic males have cryptorchidism, viable Wolffian duct structures, female or ambiguous genitalia, no Müllerian duct structures
  • Testes resemble cryptorchid testes
  • May have bilateral Leydig cell hyperplasia with deficiencies of 21-hydroxylase, 11β hydroxylase, 17α hydroxylase, 3β hydroxysteroid dehydrogenase
  • Treat with corticosteroids or surgical excision of testes