Aggressive angiomyxoma

Testis and epididymis
Spermatic cord tumors
Aggressive angiomyxoma

Author: Rafael Jimenez, M.D. (see Authors page)

Revised: 31 May 2017, last major update March 2012

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PubMed Search: aggressive angiomyxoma spermatic cord

Table of Contents

Definition / general | Gross description | Microscopic (histologic) description | Positive stains | Negative stains

Cite this page: Aggressive angiomyxoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/testisaggangiomyxoma.html. Accessed July 15th, 2017.

Definition / general

Locally aggressive but nonmetastasizing soft tissue tumor of pelvic soft tissue and perineum, almost always in adult women
Case report of tumors in 4 men (Am J Surg Pathol 1992;16:1059)
Local recurrence common but does not metastasize

Gross description

Myxoid, nonencapsulated

Microscopic (histologic) description

Infiltrative tumors composed of fibromyxoid matrix with occasional bland spindle cells with delicate cytoplasmic processes in background of scattered vessels of variable size, some with hypertrophy or hyalinization of vessel wall

Positive stains

vimentin, variable muscle specific actin, alpha smooth muscle actin and desmin

Negative stains

S100