Spermatic granuloma (epididymitis nodosa)

Testis and epididymis
Nonneoplastic lesions
Spermatic granuloma (epididymitis nodosa)

Author: Rafael Jimenez, M.D. (see Authors page)

Revised: 5 June 2017, last major update March 2012

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PubMed Search: Spermatic granuloma[title]

Table of Contents

Definition / general | Gross description | Microscopic (histologic) description | Differential diagnosis

Cite this page: Spermatic granuloma (epididymitis nodosa). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/testisepidspermgran.html. Accessed July 15th, 2017.

Definition / general

Resembles vasitis nodosa
Causes: inflammation or trauma damage epithelium or basement membrane, causing spillage of spermatozoa into interstitium (similar to vasitis nodosa) and resulting granulomatous inflammation
References: Arch Pathol Lab Med 1986;110:61

Gross description

Nodule up to 3 cm in head of epididymis

Microscopic (histologic) description

Noncaseating granulomas around spermatozoa

Differential diagnosis

Histoplasma capsulate