Testis and epididymis
Infertility
Excurrent duct obstruction

Author: Turki Al-Hussain, M.D. (see Authors page)

Revised: 4 April 2017, last major update September 2012

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PubMed Search: Excurrent duct obstruction

Cite this page: Excurrent duct obstruction. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/testisexcurrentduct.html. Accessed June 27th, 2017.
Definition / general
  • Excurrent means distal to rete testis
  • Congenital or acquired
  • Occurs in 10% of biopsies for infertility
  • Associated with azoospermia, normal sized testes and active (but not necessarily normal) spermatogenesis (Am J Surg Pathol 1999;23:1546)
  • Congenital: agenesis or atresia of epididymis or vas deferens, atrophy from secretions in cystic fibrosis
  • Acquired: infection, sterilization, inadvertent surgical ligation of vas deferens
  • Partial excurrent duct obstruction is likely if sperm count is appreciably lower than that expected from biopsy
Microscopic (histologic) description
  • Active spermatogenesis, germ cell disorganization and sloughing
  • Variable interstitial fibrosis and sperm granulomas
  • No tubular basement membrane thickening