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Testis and epididymis
Sex cord stromal tumors
Fibromas

Reviewer: Swapnil U. Rane, M.D. (see Reviewers page)
Revised: 20 June 2013, last major update June 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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Terminology
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Epidemiology
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Etiology
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Clinical features
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Case reports
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Treatment
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Gross description
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Gross images
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Various images

Micro description
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Micro images
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Figures A-F

Spindle cells arranged in storiform and herringbone pattern

Unencapsulated and circumscribed appearance


A, The tumor is well-circumscribed with an inconspicuous fibrous capsule and surrounded by atrophic seminiferous tubules (hematoxylin-eosin [H&E] stain 40).
B, Tumor is composed of epithelioid round cells in vague cords and small nests separated by collagen fibers, mimicking a metastatic adenocarcinoma (H&E stain 100).
C, Tumor cells have round-oval nuclei with small distinct nucleoli and fine, regularly dispersed chromatin. Pale granular cytoplasm with variable-sized vacuoles push nuclei to periphery; resemble signet-ring cells (H&E stain 400).
D, A few intracytoplasmic eosinophilic hyaline globules can be seen. These eosinophilic globules resemble extracellular collagen bundles (H&E stain 1000).
E and F, Tumor cells were immunoreactive for vimentin (E) and CD99 (F).


Positive stains
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Negative stains
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Electron microscopy description
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Molecular / cytogenetics description
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Differential diagnosis
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Additional references
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End of Testis and epididymis > Sex cord stromal tumors > Fibromas


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