Testis and epididymis
Infectious testicular lesions
Reviewer: Sean Williamson, M.D. (see Reviewers page)
Revised: 20 April 2013, last major update December 2012
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
- Does not occur in U.S.
- Rarely presents with orchitis (Am J Clin Pathol 1980;73:712)
- Testicular involvement thought to be facilitated by lower temperature of scrotum
- 3 phases of testicular involvement:
- Vascular phase: blood vessels show perivascular lymphocytic inflammation and interstitium is filled with macrophages containing mycobacteria
- Interstitial phase: endarteritis, Leydig cell clusters, interstitial fibrosis, histiocytes containing acid-fast bacteria and reduced spermatogenesis
- Obliterative phase: dense fibrosis, no detectable tubules, reduced vessels, rare acid-fast bacteria; associated with gynecomastia and infertility
End of Testis and epididymis > Infectious testicular lesions > Leprosy
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