Testis and epididymis
Nonneoplastic testicular lesions

Author: Sean Williamson, M.D. (see Authors page)

Revised: 7 April 2017, last major update December 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Malakoplakia [title] testis

Cite this page: Malakoplakia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/testismalakoplakia.html. Accessed April 25th, 2017.
Definition / General
  • Affects testis alone or testis and epididymis
  • Culture often grows presence of coliforms
Gross Description
  • Testis is enlarged, tanish yellowy brown
  • Associated with abscesses and thrombosed blood vessels
Micro Description
  • Tubular atrophy, sheets of histiocytes with Michaelis-Gutmann bodies (intracellular and extracellular round structures containing iron and calcium)
Micro Images

Images hosted on other servers:

Tubular outlines appear preserved

Tubular architecture is destroyed

Sertoli cells replaced

Malakoplakia of the testis

Virtual Slides

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Malakoplakia of testis

Electron Microscopy Description
  • Bacteria within phagolysosomes of histiocytes