Testis & paratestis
Ovarian type tumors
Mucinous cystadenocarcinoma
Author: Jennifer B. Gordetsky, M.D.
Last author update: 1 January 2014
Last staff update: 28 March 2022
Copyright: 2003-2024, PathologyOutlines.com, Inc.
PubMed Search: Mucinous adenocarcinoma testis
Table of Contents
Definition / general | Epidemiology | Pathophysiology | Diagnosis | Case reports | Treatment | Clinical images | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Negative stains | Differential diagnosisCite this page: Gordetsky J. Mucinous cystadenocarcinoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/testismucincystadenoca.html. Accessed April 19th, 2024.
Definition / general
- Ovarian type surface epithelial carcinoma of the testis with mucinous differentiation
Epidemiology
- Extremely rare testicular tumor reported in middle age and elderly men (mean age 62)
Pathophysiology
- The histogenesis of the ovarian type surface epithelial tumors of the testis and paratestis remains unclear
- These tumors are possibly derived from Müllerian remnants or by metaplasia of the mesothelium of the tunica vaginalis (Hum Pathol 2011;42:1343)
Diagnosis
- Clinical evaluation is necessary to rule out metastatic spread from a primary adenocarcinoma of the appendix, colon, stomach, pancreas, lung or prostate
Case reports
- 55 year old man with primary testicular mucinous neoplasms (Can Urol Assoc J 2010;4:E112)
- 59 year old man with bilateral mucinous cystadenocarcinoma of the testis and epididymis (Arch Pathol Lab Med 1992;116:1360)
- 71 year old man with mucinous cystadenocarcinoma of the testis (Hum Pathol 2011;42:1343)
Treatment
- Radical orchiectomy
Clinical images
Images hosted on other servers:
Right testicular borderline mucinous tumor
Gross description
- Mucinous, cystic mass replacing the testicular parenchyma
Microscopic (histologic) description
- Well to moderately differentiated malignant cystic neoplasm with mucinous differentiation
- Back to back irregular glands, elongated fine complex papillary structures lined with alternating goblet cells and ciliated cells, with little intervening stroma
- Papillary structures have atypical cells with hyperchromatic overlapping elongated nuclei with coarse chromatin and increased nuclear to cytoplasmic ratio
- Cystic spaces filled with mucin, fibrinopurulent material, degenerative cellular debris
- Psammomatous calcifications can be present as well as mucin extravasation
Microscopic (histologic) images
Images hosted on other servers:
Cyst wall irregularly thickened and fibrotic
Mucinous epithelium
resembling endocervical
type cells
