Testis and epididymis
Nonneoplastic lesions
Radiation effect



Topic Completed: 1 December 2012

Revised: 27 March 2019

Copyright: 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: "radiation effect" testicular

Sean R. Williamson, M.D.
Page views in 2018: 75
Page views in 2019 to date: 49
Table of Contents
Definition / general
Cite this page: Williamson S. Radiation effect. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/testisradiation.html. Accessed August 25th, 2019.
Definition / general
  • Germ cells have variable sensitivity to radiation - type B spermatogonia are most sensitive, spermatids are least sensitive
  • Therapeutic radiation may cause only temporary infertility with recovery in 30 - 80 weeks, delayed if combined with chemotherapy
  • Radiation for intratubular germ cell neoplasia causes germ cell aplasia
  • Radiation exposure at Hiroshima and Nagasaki, Japan in 1945 caused increased tubular sclerosis, vascular hyalinization
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