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Testis and epididymis
Germ cell tumors
Seminoma

Reviewer: Turki Al-Hussain, M.D. (see Reviewers page)
Revised: 21 April 2013, last major update January 2013
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.

See variants below

General
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Clinical features
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Case reports
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Treatment
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Gross description
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Gross images
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Very large seminoma

Cream-colored, soft, fleshy, multinodular tumor

Seminoma

Lobulated soft tan to brown tissue

Soft pink-tan nodules

Micro description
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Micro images
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Normal testis on left, seminoma on right

Histologic pattern of typical seminoma

Interstitial growth pattern

Diffuse sheets of tumor cells

Lymphocytic infiltrate in fibrous trabeculae

Lymphocytic infiltrate surrounding clusters of tumor cells


Cytoplasm of seminoma cells

Florid lymphoid reaction

Tumor cells infiltrate interstitium

Large and small ghostlike necrotic cells

LIN28+

OCT4+

Positive stains
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Negative stains
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Electron microscopy description
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Variants

General
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Case reports
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End of Testis and epididymis > Germ cell tumors > Seminoma


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