Testis and epididymis
Sex cord stromal tumors
Sertoli cell tumors

Author: Swapnil U. Rane, M.D. (see Authors page)

Revised: 13 June 2017, last major update October 2013

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: Sertoli cell tumors [title]
Cite this page: Sertoli cell tumors. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/testissertoli.html. Accessed August 20th, 2018.
Definition / general
  • ~1% of testicular tumors in all age groups
  • Occurs in children (~15% of cases) and middle aged adults; 10% are malignant in both groups
  • Can occur as part of androgen insensitivity syndrome, Carneys complex and Peutz-Jeghers syndrome (Am J Surg Pathol 1995;19:50)
Clinical features
  • Testicular mass in normally descended testis
  • Feminization and gynecomastia in ~25 - 30% of cases
Case reports
  • Orchidectomy is treatment of choice