Testotoxicosis

Testis and epididymis
General
Testotoxicosis

Author: Turki Al-Hussain, M.D. (see Authors page)

Revised: 4 April 2017, last major update August 2012

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PubMed Search: Testotoxicosis

Table of Contents

Definition / general | Microscopic (histologic) description

Cite this page: Testotoxicosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/testistestotox.html. Accessed July 15th, 2017.

Definition / general

Form of male sexual precocity with active Leydig cell differentiation and premature onset of spermatogenesis without pituitary gonadotropin stimulation (Arch Pathol Lab Med 1985;109:990)
Due to apparent inherited intratesticular defect

Microscopic (histologic) description

Leydig cells appear fully differentiated
No Reinke crystals
Germ cells at all stages of spermatogenesis present but with disordered maturation
Structural abnormalities in spermatids