Testis and epididymis
Non-neoplastic testicular lesions
Reviewer: Sean Williamson, M.D. (see Reviewers page)
Revised: 21 April 2013, last major update December 2012
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
- Abnormal dilation and tortuosity of veins in pampiniform plexus of spermatic cord, probably due to insufficiency of venous valves
- Often associated with infertility; after treatment, 40-55% are fertile
- 90% on left; 10% bilateral
- Isolated right sided varicocele is associated with situs inversus, venous thrombosis or venous compression from space occupying lesion
- Adolescent varicocele: pathologic changes found at or soon after puberty, consisting of tubular sclerosis, premature germ cell sloughing, small vessel sclerosis and variable hypospermatogenesis (Am J Clin Pathol 1988;89:321)
- Ligation or occlusion of left spermatic vein
- Variable thickening of venous wall with fibrosis, decreased spermatogenesis in tubules with germ cell degeneration and increased Leydig cells
End of Testis and epididymis > Non-neoplastic testicular lesions > Varicocele
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